| 2022-10-03 MLB | Toronto Blue Jays at Baltimore Orioles | Baltimore Orioles | 1.5 | L |
| 2022-10-03 NFL | Los Angeles Rams at San Francisco 49ers | San Francisco 49ers | -120 | W |
| 2022-10-03 NFL | Los Angeles Rams at San Francisco 49ers | San Francisco 49ers | -2 | W |
| 2022-10-03 MLB | Tampa Bay Rays at Boston Red Sox | Boston Red Sox | 126 | W |
| 2022-10-03 MLB | Tampa Bay Rays at Boston Red Sox | Boston Red Sox | 1.5 | W |
| 2022-10-03 MLB | Toronto Blue Jays at Baltimore Orioles | Baltimore Orioles | 116 | L |
| 2022-10-02 CFB | SMU at Central Florida | SMU | 3 | L |
| 2022-10-02 NFL | New York Jets at Pittsburgh Steelers | New York Jets | 3.5 | W |
| 2022-10-02 MLB | Philadelphia Phillies at Washington Nationals | Philadelphia Phillies | -225 | W |
| 2022-10-02 MLB | Boston Red Sox at Toronto Blue Jays | Boston Red Sox | 1.5 | L |
| 2022-10-02 MLB | Kansas City Royals at Cleveland Guardians | Cleveland Guardians | -220 | W |
| 2022-10-02 MLB | Pittsburgh Pirates at St Louis Cardinals | Pittsburgh Pirates | 1.5 | W |
| 2022-10-02 MLB | Chicago White Sox at San Diego Padres | Chicago White Sox | 1.5 | W |
| 2022-10-02 NFL | Seattle Seahawks at Detroit Lions | Seattle Seahawks | 3.5 | W |
| 2022-10-01 CFB | UL Monroe at Arkansas State | UL Monroe | 7 | L |
| 2022-10-01 CFB | Wake Forest at Florida State | Wake Forest | 6.5 | W |
| 2022-10-01 CFB | California at Washington State | Washington State | -180 | W |
| 2022-10-01 CFB | NC State at Clemson | NC State | 7 | L |
| 2022-10-01 CFB | Purdue at Minnesota | Purdue | 9.5 | W |
| 2022-10-01 MLB | Kansas City Royals at Cleveland Guardians | Kansas City Royals | 1.5 | W |
| 2022-10-01 MLB | Arizona Diamondbacks at San Francisco Giants | Arizona Diamondbacks | 108 | W |
| 2022-10-01 CFB | Oklahoma at TCU | Oklahoma | -205 | L |
| 2022-10-01 CFB | Alabama at Arkansas | Arkansas | 17 | L |
| 2022-10-01 CFB | SMU at Central Florida | SMU | 3.5 | L |
| 2022-10-01 MLB | Arizona Diamondbacks at San Francisco Giants | Arizona Diamondbacks | 1.5 | W |
| 2022-10-01 MLB | Cincinnati Reds at Chicago Cubs | Cincinnati Reds | 1.5 | W |
| 2022-10-01 CFB | Oregon State at Utah | Oregon State | 10.5 | L |
| 2022-10-01 CFB | Michigan State at Maryland | Michigan State | 7.5 | L |
| 2022-10-01 MLB | Pittsburgh Pirates at St Louis Cardinals | Pittsburgh Pirates | 1.5 | L |
| 2022-10-01 CFB | Kentucky at Mississippi | Kentucky | 6.5 | W |
| 2022-10-01 CFB | Rutgers at Ohio State | Rutgers | 39.5 | W |
| 2022-10-01 CFB | Troy at Western Kentucky | Troy | 5.5 | W |
| 2022-10-01 CFB | San Jose State at Wyoming | Wyoming | 2.5 | L |
| 2022-10-01 CFB | Florida International at New Mexico State | Florida International | 14.5 | W |
| 2022-10-01 CFB | Colorado at Arizona | Colorado | 17.5 | L |
| 2022-10-01 CFB | Stanford at Oregon | Stanford | 17 | L |
| 2022-10-01 CFB | Virginia at Duke | Duke | -2.5 | W |
| 2022-10-01 CFB | Virginia at Duke | Duke | -132 | W |
| 2022-10-01 CFB | Liberty at Old Dominion | Old Dominion | 3.5 | L |
| 2022-10-01 CFB | Cincinnati at Tulsa | Tulsa | 10 | P |
| 2022-10-01 CFB | LSU at Auburn | Auburn | 8 | W |
| 2022-10-01 CFB | South Alabama at UL Lafayette | UL Lafayette | 8.5 | W |
| 2022-10-01 CFB | Florida Atlantic at North Texas | North Texas | 3 | W |
| 2022-10-01 CFB | Texas A&M at Mississippi State | Mississippi State | -195 | W |
| 2022-10-01 CFB | Ohio at Kent State | Ohio | 11.5 | W |
| 2022-10-01 CFB | Massachusetts at Eastern Michigan | Massachusetts | 19.5 | W |
| 2022-10-01 CFB | Iowa State at Kansas | Iowa State | -160 | L |
| 2022-09-30 MLB | Kansas City Royals at Cleveland Guardians | Kansas City Royals | 115 | L |
| 2022-09-30 MLB | Boston Red Sox at Toronto Blue Jays | Toronto Blue Jays | -181 | W |
| 2022-09-30 MLB | Kansas City Royals at Cleveland Guardians | Kansas City Royals | 1.5 | L |
| 2022-09-30 MLB | Minnesota Twins at Detroit Tigers | Minnesota Twins | -141 | W |
| 2022-09-30 MLB | Baltimore Orioles at New York Yankees | Baltimore Orioles | 1.5 | W |
| 2022-09-30 CFB | Tulane at Houston | Tulane | 120 | W |
| 2022-09-30 CFB | UTSA at Middle Tenn State | UTSA | -180 | W |
| 2022-09-30 CFB | Tulane at Houston | Tulane | 2.5 | W |
| 2022-09-30 MLB | Philadelphia Phillies at Washington Nationals | Philadelphia Phillies | -177 | W |
| 2022-09-29 NFL | Miami Dolphins at Cincinnati Bengals | Miami Dolphins | 3.5 | L |
| 2022-09-29 MLB | Baltimore Orioles at Boston Red Sox | Baltimore Orioles | 1.5 | L |
| 2022-09-29 MLB | Chicago White Sox at Minnesota Twins | Chicago White Sox | -110 | W |
| 2022-09-29 MLB | Philadelphia Phillies at Chicago Cubs | Philadelphia Phillies | -184 | L |
| 2022-09-28 MLB | Baltimore Orioles at Boston Red Sox | Baltimore Orioles | 1.5 | L |
| 2022-09-28 MLB | Chicago White Sox at Minnesota Twins | Chicago White Sox | -111 | L |
| 2022-09-27 MLB | Baltimore Orioles at Boston Red Sox | Boston Red Sox | -125 | W |
| 2022-09-27 MLB | Texas Rangers at Seattle Mariners | Texas Rangers | 1.5 | W |
| 2022-09-27 MLB | Colorado Rockies at San Francisco Giants | San Francisco Giants | -175 | W |
| 2022-09-27 MLB | Los Angeles Dodgers at San Diego Padres | San Diego Padres | 1.5 | W |
| 2022-09-27 MLB | Chicago White Sox at Minnesota Twins | Chicago White Sox | -116 | L |
| 2022-09-27 MLB | Kansas City Royals at Detroit Tigers | Kansas City Royals | 1.5 | W |
| 2022-09-27 MLB | St Louis Cardinals at Milwaukee Brewers | St Louis Cardinals | 1.5 | W |
